FILE MICRORNAS

Another approach is included in the DNA RNA small to evaluate (miRNAs).
Myrna small (24-18 nucleotides) are recently discovered class of nucleic acids.
Negative gene expression (107) to organize. This new class of regulatory molecules
A wide range of proliferation and differentiation of human cancer (107).
The number of new research, such as the following, indicating that the miRNA can act as oncogene
Of the tumor suppressor genes, or sometimes both (108). Analysis of high productivity
It was found that miRNA expression is regulated in many cases, human
Cancer (109 1011 hundred not), including cancer (107). However, a lot of controversy
Are still relevant to the best miRNA signatures specific to cancer cells
Analysis platform (107) and seems to depend on the size of type.
In cancer, miRNA profiling appears to correlate with disease outcome
(109 and 111). Real-time reverse transcription - PCR, is used Liu. (111) have been identified
MiRNA signature non-small cell lung cancer five years, the provision of therapeutic effect. Of these
Study showed patients at high risk of signing the voting public Myrna poor
And disease-free survival of low degree of risk (111) compared with the patients.
In addition, miRNA has been shown to modify the number of critical periods
Of lung cancer. Weiss et al. Showed that the loss of 128 B - is located (112) on the chromosome, and Myrna
Associated regulator of EGFR and estimates with the 3P response to the target
Dam EGFR. Myrna room for the impact of intensive research.
Pathogenesis and treatment of lung cancer.