THE MAJORITY OF SQUAMOUS CELL CARCINOMA SUGGESTS A GENETIC ABNORMALITY

 

Of EGFR and KRAS gene mutations, with the exception exists in the lung NSCLCs adenocarcinomas (Table 2), (1, 25) has more. However, squamous cell carcinoma EGFR expression in carcinomas of the very high frequency (84%) characterized by By immunohistochemical methods (39) is determined by the disruption of TP53 and RB gene pathways squamous cell carcinoma (1) are common. Most tumors show Much of the deleted chromosome 3P (15). Recently, it has LKB1 mutations mithayeo shows the deactivation of tumor suppressor genes Remove all relatively common occurrence of squamous cell carcinoma (19%) are Lung adenocarcinomas (34%) (60).