molecular pathology of adenocarcinoma

the rapid expansion of technologies available to examine adenocarcinomas
during the past 2 decades has led to the deciphering
of complex molecular pathology that drives growth and
metastases of these tumors. the molecular abnormalities of
adenocarcinoma are not only of intrinsic biological interest
but also provide targets for therapeutic intervention and can
be used to predict response to new targeted agents. molecular
pathology is probably better defined for adenocarcinoma than
for other tumor types because of its high frequency, surgical
accessibility, and heterogeneity and because of the early success
in identifying clinically important molecular pathways in this
tumor type: