Senin, 23 Juli 2012

Bone metastases lung cancer will metastasize to almost any bone

 Bone metastases lung cancer will metastasize to almost
any bone, though the axial skeleton and proximal long bones
are most commonly concerned. bone pain is present in up to
25% of all lung cancer patients at presentation. in lung cancer,
positron emission tomography (pet) scans have similar
sensitivity to isotope bone scans though less specificity. 77
thus, patients with pet scans that don't show any abnormality
in bones, and don't have any signs or symptoms suggestive
of metastases, don't want a further bone scan. in patients
with bone metastases, radiograph analysis of weight-bearing
bones might be necessary to detect the risk of and prevent
pathologic fractures. most symptomatic bone metastases in
lung cancer patients are treated with radiation therapy. in selected
patients with weight-bearing bony metastases, surgical
choices might be thought-about. 78, 79
patients with bone metastases might require significant
pain medications. pain connected to bone metastases might respond
well to nonsteroidal anti-inflammatory medication (nsaids)
and ought to be thought-about in a veryddition to narcotic analgesics.
recent information suggests that the new generation nitrogen-containing
bisphosphonate, zoledronic acid, has clinical benefits
in solid tumor patients with bone metastases, together with lung
cancer patients. in a very randomized study that included nsclc
patients, zoledronic acid considerably decreased the incidence
of skeletal- connected events and that increased the time to the primary
skeletal- connected event. eighty there are conjointly information to recommend that the
addition of bisphosphonates to radiation therapy for bone metastases
was beneficial.

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